Toward Minimal Residual Disease-Directed Therapy in Melanoma

Minimal residual disease in melanoma.

A number of specific genes encoding for melanosomal proteins are selectively expressed in melanocytes and melanomas. For detection of circulating melanoma cells, the expression of the tyrosinase gene is most widely used. Several cohorts of melanoma patients from single institutions have been analyzed by various research groups for the presence of circulating melanoma cells in all stages of dise...

Evidence-Based Focused Review Minimal residual disease–directed therapy in acute myeloid leukemia

Department of Internal Medicine V, University Hospital of Heidelberg, Heidelberg, Germany; Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany; Department of Medical and Molecular Genetics, King’s College London, Faculty of Life Sciences and Medicine, London, United Kingdom; Buffalo Medical Group, Buffalo, NY; Clinical Research Division, Fred Hutchinson Cancer Research...

Minimal residual disease-guided therapy in childhood acute lymphoblastic leukemia.

Minimal residual disease in pediatric ALL

Minimal residual disease in acute leukemia.

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